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Nat Methods. 2005 Aug;2(8):599-605.
A microfluidic culture platform for CNS axonal injury, regeneration and transport.
Taylor AM, Blurton-Jones M, Rhee SW, Cribbs DH, Cotman CW, Jeon NL. |
| Investigation of axonal biology in the central nervous system (CNS) is hindered by a lack of an appropriate in vitro method to probe axons independently from cell bodies. Here we describe a microfluidic culture platform that polarizes the growth of CNS axons into a fluidically isolated environment without the use of targeting neurotrophins. Complete Reference |
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Proc Natl Acad Sci U S A. 2011 Jul 5;108(27):11246-51. Epub 2011 Jun 20.
Neurotrophin-mediated dendrite-to-nucleus signaling revealed by microfluidic compartmentalization of dendrites.
Cohen MS, Orth CB, Kim HJ, Jeon NL, Jaffrey SR.
SourceDepartment of Pharmacology, Weill Medical College Cornell University, New York, NY 10065, USA. |
Cell Death Differ. 2011 Aug 5. doi: 10.1038/cdd.2011.105. [Epub ahead of print]
Lanosterol induces mitochondrial uncoupling and protects dopaminergic neurons from cell death in a model for Parkinson's disease.
Lim L, Jackson-Lewis V, Wong LC, Shui GH, Goh AX, Kesavapany S, Jenner AM, Fivaz M, Przedborski S, Wenk MR.
SourceDepartment of Biological Sciences, National University of Singapore, Singapore. |
Vet Microbiol. 2011 Sep 28;152(3-4):270-9. Epub 2011 May 13.
The bovine herpesvirus type 1 envelope protein Us9 acidic domain is crucial for anterograde axonal transport.
Chowdhury SI, Brum MC, Coats C, Doster A, Wei H, Jones C.
SourceDepartment of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70803, United States. |
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Mol Cell Neurosci. 2011 Oct;48(2):142-50. Epub 2011 Jul 21.
IL-1β inhibits axonal growth of developing sympathetic neurons.
Nolan AM, Nolan YM, O'Keeffe GW. |
Curr Opin Neurobiol. 2010 Oct;20(5):640-7. Epub 2010 Aug 23.
Micro-scale and microfluidic devices for neurobiology.
Taylor AM, Jeon NL. |
Lab Chip. 2010 Aug 21;10(16):2083-92. Epub 2010 Jun 9.
Examination of axonal injury and regeneration in micropatterned neuronal culture using pulsed laser microbeam dissection.
Hellman AN, Vahidi B, Kim HJ, Mismar W, Steward O, Jeon NL, Venugopalan V.
SourceDepartment of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA. |
J Virol. 2011 Mar 30. [Epub ahead of print]
Anterograde transport of herpes simplex virus capsids in neurons by both Separate and Married mechanisms.
Wisner TW, Sugimoto K, Howard PW, Kawaguchi Y, Johnson DC.
Department of Molecular Microbiology & Immunology, Oregon Health & Sciences University, Portland, OR 97239; Division of Viral Infection, Department of Infectious Disease Control, The University of Tokyo, Tokyo, 108-8639, Japan. |
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