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Nat Methods. 2005 Aug;2(8):599-605.
A microfluidic culture platform for CNS axonal injury, regeneration and transport.
Taylor AM, Blurton-Jones M, Rhee SW, Cribbs DH, Cotman CW, Jeon NL. |
| Investigation of axonal biology in the central nervous system (CNS) is hindered by a lack of an appropriate in vitro method to probe axons independently from cell bodies. Here we describe a microfluidic culture platform that polarizes the growth of CNS axons into a fluidically isolated environment without the use of targeting neurotrophins. Complete Reference |
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| Additional References |
Neuron. 2010 Apr 15;66(1):57-68.
Microfluidic local perfusion chambers for the visualization and manipulation of synapses.
Taylor AM, Dieterich DC, Ito HT, Kim SA, Schuman EM. |
Neuron. 2009 Mar 26;61(6):880-94.
Presynaptic regulation of astroglial excitatory neurotransmitter transporter GLT1.
Yang Y, Gozen O, Watkins A, Lorenzini I, Lepore A, Gao Y, Vidensky S, Brennan J, Poulsen D, Won Park J, Li Jeon N, Robinson MB, Rothstein JD. |
J Nanosci Nanotechnol. 2009 Dec;9(12):7330-5.
Shear stress effect on transfection of neurons cultured in microfluidic devices.
Shin HS, Kim HJ, Sim SJ, Jeon NL. |
PLoS ONE. 2008 Jun 18;3(6):e2382.
A microfluidic chamber for analysis of neuron-to-cell spread and axonal transport of an alpha-herpesvirus.
Liu WW, Goodhouse J, Jeon NL, Enquist LW. |
Nat Cell Biol. 2009 Aug;11(8):1024-30. Epub 2009 Jul 20.
Axonal elongation triggered by stimulus-induced local translation of a polarity complex protein.
Hengst U, Deglincerti A, Kim HJ, Jeon NL, Jaffrey SR. |
Methods Mol Biol. 2006;321:167-77.
Microfluidic chambers for cell migration and neuroscience research.
Taylor AM, Rhee SW, Jeon NL. |
Biotechnol J. 2009 Nov;4(11):1573-7.
Novel microfluidic platform for culturing neurons: culturing and biochemical analysis of neuronal components.
Park JW, Kim HJ, Byun JH, Ryu HR, Jeon NL.
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Nat Protoc. 2006;1(4):2128-36.
Microfluidic culture platform for neuroscience research.
Park JW, Vahidi B, Taylor AM, Rhee SW, Jeon NL. |
Neurobiol Aging. 2009 Jun 18. [Epub ahead of print]
beta-Amyloid impairs axonal BDNF retrograde trafficking.
Poon WW, Blurton-Jones M, Tu CH, Feinberg LM, Chabrier MA, Harris JW, Jeon NL, Cotman CW. |
Nat Methods. 2005 Aug;2(8):599-605.
A microfluidic culture platform for CNS axonal injury, regeneration and transport.
Taylor AM, Blurton-Jones M, Rhee SW, Cribbs DH, Cotman CW, Jeon NL.
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J Neurosci. 2009 Apr 15;29(15):4697-707.
Axonal mRNA in uninjured and regenerating cortical mammalian axons.
Taylor AM, Berchtold NC, Perreau VM, Tu CH, Li Jeon N, Cotman CW.
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